Csk Polyclonal Antibody for Rat(Rattus norvegicus) | EIAab.comCsk Polyclonal Antibody for Rat(Rattus norvegicus)

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Index > Protein center > Csk(Gene name) > Rat

Csk (Gene name),

Tyrosine-protein kinase CSK (Protein name ), CSK_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Csk;

Protein name:

Tyrosine-protein kinase CSK;

Alternative:

C-Src kinase;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with phosphorylated SIT1, LIME1 and TGFB1I1. Interacts with PTPN8. Interacts with SRCIN1 (By similarity). Interacts with phosphorylated PAG1.

Function:

Specifically phosphorylates 'Tyr-504' on LCK, which acts as a negative regulatory site. Can also act on the LYN and FYN kinases.

Subcellular Location:

Cytoplasm Cell membrane Mainly cytoplasmic, also present in lipid rafts.

Protein Attributes:

Sequence length:

450

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

P32577

UniGene:

Rn.2759

KEGG:

rno:315707

Pfam:

PF07714

STRING:

10116.ENSRNOP00000026358

String:

P32577

Uniprot:

P32577

FOR

ELISA Kit for Rat Tyrosine-protein kinase CSK

Cat.:

E11982h

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Packing:

96T

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ELISA Kit for Rat Tyrosine-protein kinase CSK

MSDS:

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ELISA Kit for Rat Tyrosine-protein kinase CSK

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ELISA Kit for Rat Tyrosine-protein kinase CSK

Cat.:

E11982m

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Packing:

96T

ELISA Kit for Rat Tyrosine-protein kinase CSK

Cat.:

E11982r

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Packing:

96T

CLIA Kit for Rat Tyrosine-protein kinase CSK

Cat.:

U11982m

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MSDS:

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Packing:

96T

CLIA Kit for Rat Tyrosine-protein kinase CSK

MSDS:

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CLIA Kit for Rat Tyrosine-protein kinase CSK

MSDS:

Please sign in first.

CLIA Kit for Rat Tyrosine-protein kinase CSK

Cat.:

U11982h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Rat Tyrosine-protein kinase CSK

Cat.:

U11982r

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Packing:

96T

Polyclonal Antibody for Rat Tyrosine-protein kinase CSK

Cat.:

P11982Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Tyrosine-protein kinase CSK

Monoclonal Antibody for Rat Tyrosine-protein kinase CSK

Protein for Rat Tyrosine-protein kinase CSK

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Cloning of a complementary DNA for a protein-tyrosine kinase that specifically phosphorylates a negative regulatory site of p60c-src."
Nada S. , Okada M. , McAuley A. , Cooper J.A. , Nakagawa H.
Nature351:69-72(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Thymus.
3.

"CSK: a protein-tyrosine kinase involved in regulation of src family kinases."
Okada M. , Nada S. , Yamanashi Y. , Yamamoto T. , Nakagawa H.
J. Biol. Chem.266:24249-24252(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN PHOSPHORYLATION OF LYN AND FYN
4.

"Regulation of c-Fgr protein kinase by c-Src kinase (CSK) and by polycationic effectors."
Ruzzene M. , James P. , Brunati A.M. , Donella-Deana A. , Pinna L.A.
J. Biol. Chem.269:15885-15891(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN PHOSPHORYLATION OF FGR
5.

"Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases."
Kawabuchi M. , Satomi Y. , Takao T. , Shimonishi Y. , Nada S. , Nagai K. , Tarakhovsky A. , Okada M.
Nature404:999-1003(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PAG1
6.

"Mechanism of Csk-mediated down-regulation of Src family tyrosine kinases in epidermal growth factor signaling."
Matsuoka H. , Nada S. , Okada M.
J. Biol. Chem.279:5975-5983(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PAG1

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